Description

α-Melanotrophin CAS NO 37213-49-3 is a synthetic peptide hormone that replicates the activity of the endogenous α-melanocyte-stimulating hormone (α-MSH). This compound is critical for research and development in advanced biomedical fields due to its role in regulating pigmentation, inflammation, and energy homeostasis. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and biotechnology companies focused on endocrinology, dermatology, and metabolic disorder therapeutics.

Application

• Pharmaceutical Research & Development: Serves as a key reference standard and active ingredient in the development of novel therapeutics targeting skin disorders, obesity, and inflammatory diseases.
• Biochemical & Physiological Studies: Used in laboratory settings to study melanocortin receptor (MCR) signaling pathways, appetite regulation, and anti-inflammatory mechanisms.
• Cosmeceutical R&D: Investigated for potential applications in topical formulations aimed at skin pigmentation modulation and anti-aging products.
• Academic Research: Essential for in vitro and in vivo studies in university and institutional labs focusing on endocrinology and peptide biology.
• Peptide Synthesis & Custom Manufacturing: Used as a building block or target molecule for companies specializing in custom peptide synthesis and GMP-grade manufacturing.

Basic Information

Product Name	α-Melanotrophin
CAS No.	37213-49-3
Molecular Formula	C77H109N21O19S
Molecular Weight	1664.9 g/mol
Synonyms	α-Melanocyte-Stimulating Hormone; α-MSH; α-MSH; Ac-Ser-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val-NH2; Melanotropin alpha; Intermedin; Afamelanotide (related analog); [N-Acetyl-Ser1]-α-MSH
EINECS	Contact for details

Quality Control

Our α-Melanotrophin is manufactured under stringent controls to ensure high purity and batch-to-batch consistency, suitable for research and development purposes. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. While produced to exacting internal standards, specifications can be aligned with client requirements for advanced applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive); allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC & MS)	Conforms to reference standard
Assay (HPLC)	≥ 95.0%
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%
Peptide Content	≥ 80.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.