Description

Warfarin Related Compound A (50 Mg) (3-(o-Hydroxyphenyl)-5-Phenyl-2-Cyclohexen-1-One) is a high-purity analytical reference standard critical for pharmaceutical research and quality control. This compound serves as a key impurity marker and structural analog in the analysis of the widely used anticoagulant drug, Warfarin. It is essential for laboratories requiring precise method development, validation, and regulatory compliance testing. Pharmaceutical manufacturers, contract research organizations (CROs), and analytical testing facilities rely on this standard to ensure product safety and efficacy.

Application

• Pharmaceutical Impurity Profiling and Identification in Warfarin sodium and related anticoagulant APIs.
• Method Development and Validation for HPLC, UPLC, and GC analytical procedures in QC laboratories.
• Stability Indicating Method (SIM) studies to monitor degradation products in drug formulations.
• Pharmacopoeial Testing as a system suitability and reference compound for compendial methods (e.g., USP, EP).
• Regulatory Submission Support, providing certified reference material for FDA, EMA, and ICH guideline compliance.
• Academic and Clinical Research into the metabolism, pharmacokinetics, and structure-activity relationships of coumarin derivatives.
• Calibration Standard for quantitative analysis to determine impurity levels in active pharmaceutical ingredients (APIs).

Basic Information

Product Name	Warfarin Related Compound A (50 Mg) (3-(o-Hydroxyphenyl)-5-Phenyl-2-Cyclohexen-1-One)
CAS No.	37209-23-7
Molecular Formula	C19H16O2
Molecular Weight	276.33 g/mol
Synonyms	3-(2-Hydroxyphenyl)-5-phenyl-2-cyclohexen-1-one; 3-(o-Hydroxyphenyl)-5-phenyl-2-cyclohexenone; Warfarin Impurity A; Warfarin Related Substance A; 2-Cyclohexen-1-one, 3-(2-hydroxyphenyl)-5-phenyl-; Benzeneacetic acid, α-phenyl-β-hydroxy-γ-oxo-, δ-lactone (related); Warfarin Lactone (impurity); o-Hydroxybenzalacetophenone cyclic lactone.
EINECS	Contact for details

Quality Control

Every batch of Warfarin Related Compound A is manufactured and analyzed under strict quality management systems. The product is supplied with a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. Our quality protocols are designed to meet the stringent requirements of pharmaceutical reference standard applications, supporting compliance with ICH Q3A/B, USP General Chapter <1086>, and EP 5.10 guidelines for impurities in new drug substances and products.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature, 15-25°C (59-77°F). The product is light-sensitive and should be handled under appropriate conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any individual impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C
Water Content (KF)	≤ 0.5% w/w

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.