Description

Convulxin is a potent, selective platelet activator and glycoprotein VI (GPVI) agonist, widely recognized in biochemical and pharmacological research. This compound is crucial for studying platelet aggregation mechanisms, thrombosis, and hemostasis in both in vitro and in vivo models. Researchers in pharmaceutical development, cardiovascular disease research, and hematology laboratories rely on its high specificity to advance therapeutic discoveries and diagnostic applications.

Application

• Platelet Research: As a selective GPVI agonist, it is a fundamental tool for inducing and studying platelet activation and aggregation in experimental settings.
• Thrombosis Models: Used to establish reliable in vitro and ex vivo models for investigating anti-thrombotic drug efficacy and mechanisms of action.
• Hemostasis Studies: Employed in research focused on understanding the intricate balance of clot formation and dissolution.
• Diagnostic Assay Development: Serves as a critical component in the development and calibration of diagnostic tests for platelet function disorders.
• Cardiovascular Pharmacology: Utilized by pharmaceutical R&D teams to screen and evaluate novel compounds targeting platelet receptors for cardiovascular therapies.
• Signal Transduction Research: Applied in cell biology to map downstream signaling pathways initiated by GPVI receptor engagement.

Basic Information

Product Name	Convulxin
CAS No.	37206-04-5
Molecular Formula	C390H620N112O118S28
Molecular Weight	Approx. 9000 g/mol (Contact for exact details)
Synonyms	Cvx; GPVI Agonist; Crotalus durissus terrificus convulxin; Platelet glycoprotein VI agonist; Snake venom C-type lectin; Convulxin from Crotalus durissus terrificus; C-type lectin convulxin; Coagulation factor X activator (from snake venom).
EINECS	Contact for details

Quality Control

Our Convulxin is produced and handled under stringent quality protocols to ensure batch-to-batch consistency and biological activity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, biological potency, and absence of endotoxins. We adhere to relevant quality standards for research-grade biochemicals to support reproducible scientific outcomes.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to reach room temperature in a desiccator before opening to prevent condensation and moisture uptake. For long-term storage, keep desiccated.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Biological Activity (Platelet Aggregation)	Fully active; EC50 provided per batch
Endotoxin Level	< 1.0 EU/mg
Solubility	Soluble in aqueous buffers or DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.