Description

2-Phenyladenosine is a chemically modified nucleoside analog of adenosine, where a phenyl group is substituted at the 2-position of the purine ring. This structural modification is of significant interest in medicinal chemistry and biochemical research, as it can alter receptor binding affinity and metabolic stability compared to the parent compound. It serves as a valuable pharmaceutical intermediate and research chemical for scientists developing novel therapeutics and studying adenosine receptor signaling pathways.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel adenosine receptor agonists and antagonists for potential drug development.
• Biochemical Research: Used as a tool compound to study the structure-activity relationships (SAR) of adenosine analogs and their interaction with A1, A2A, A2B, and A3 receptor subtypes.
• Medicinal Chemistry: Employed in lead optimization programs to enhance the potency, selectivity, and metabolic profile of candidate drug molecules targeting purinergic signaling.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Academic Research: Utilized in university and institutional labs for fundamental studies in nucleotide chemistry and cellular signaling mechanisms.

Basic Information

Product Name	2-Phenyladenosine
CAS No.	37151-14-7
Molecular Formula	C16H17N5O4
Molecular Weight	343.34 g/mol
Synonyms	2-Phenyladenosine; Adenosine, 2-phenyl-; 9-β-D-Ribofuranosyl-2-phenyladenine; 2-Phenyl-9-β-D-ribofuranosyl-9H-purin-6-amine; 2-Phenyl-9-β-D-ribofuranosyladenine; 2-PhAdo
EINECS	Contact for details

Quality Control

Our 2-Phenyladenosine is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and tests for residual solvents and moisture. A Certificate of Analysis (COA) detailing all specifications and results is provided to ensure traceability and compliance with your research or development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.