Description

3-Aminobenzamidine Dihydrochloride Hydrate is a high-purity, crystalline organic salt widely used as a key biochemical building block and research reagent. Its primary value lies in its potent and selective inhibitory activity against serine proteases, making it an essential tool for enzymatic studies and inhibitor design. This compound is critical for researchers and manufacturers in the pharmaceutical, biotechnology, and life science sectors, particularly in the development of diagnostic assays and the study of proteolytic pathways.

Application

• Serine Protease Inhibition: Acts as a potent, competitive inhibitor for trypsin, thrombin, and other trypsin-like serine proteases in biochemical research.
• Pharmaceutical Research: Serves as a crucial starting material or intermediate in the synthesis of novel therapeutic agents targeting coagulation and inflammatory disorders.
• Diagnostic Kit Development: Used in the formulation of diagnostic reagents and kits for clinical testing, particularly those involving blood coagulation and fibrinolysis pathways.
• Biochemical Assays: Employed as a standard inhibitor in enzymatic assays to study protease activity, kinetics, and mechanism of action.
• Life Science Research: A fundamental tool for cell biology and molecular biology studies investigating the role of specific proteases in cellular processes.
• Chemical Synthesis: Functions as a versatile building block for the preparation of more complex benzamidine derivatives with tailored biological activities.

Basic Information

Product Name	3-Aminobenzamidine Dihydrochloride Hydrate
CAS No.	37132-68-6
Molecular Formula	C7H12Cl2N4·xH2O
Molecular Weight	223.10 (anhydrous basis)
Synonyms	3-Aminobenzamidine Dihydrochloride; 3-Amino-Benzenecarboximidamide Dihydrochloride; m-Aminobenzamidine Dihydrochloride; 1-(3-Aminophenyl)methanimidamide Dihydrochloride; Benzamidine, 3-amino-, dihydrochloride; 3-ABD; Protease Inhibitor 3-ABD; 3-Amino-BZA·2HCl
EINECS	Contact for details

Quality Control

Our 3-Aminobenzamidine Dihydrochloride Hydrate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after use to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.