Description

[6R-[6α,7β(R*)]]-7-[(Aminophenylacetyl)Amino]-3-Methylene-8-Oxo-5-Thia-1-Azabicyclo[4.2.0]Octane-2-Carboxylic Acid Sodium Salt is a high-purity pharmaceutical intermediate and a key derivative in the synthesis of advanced β-lactam antibiotics. This compound is critical for research and development in medicinal chemistry, particularly for creating novel antibacterial agents. It is primarily utilized by pharmaceutical manufacturers, R&D laboratories, and fine chemical producers focused on developing next-generation antibiotic therapies.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel cephalosporin and penicillin-based antibiotics.
• Medicinal Chemistry Research: Used in R&D for structure-activity relationship (SAR) studies to develop new antibacterial compounds with improved efficacy.
• Active Pharmaceutical Ingredient (API) Synthesis: Serves as a precursor in the multi-step synthesis of complex β-lactam API molecules.
• Biochemical Research: Employed in studies investigating bacterial resistance mechanisms and the inhibition of penicillin-binding proteins (PBPs).
• Fine Chemical Production: Used in the manufacture of high-value, specialized chemicals for the life sciences industry.

Basic Information

Item	Details
Product Name	[6R-[6α,7β(R*)]]-7-[(Aminophenylacetyl)Amino]-3-Methylene-8-Oxo-5-Thia-1-Azabicyclo[4.2.0]Octane-2-Carboxylic Acid Sodium Salt
CAS No.	37050-97-8
Molecular Formula	C17H16N3NaO5S
Molecular Weight	397.38 g/mol
Synonyms	7-[(Aminophenylacetyl)Amino]-3-Methylene-8-Oxo-5-Thia-1-Azabicyclo[4.2.0]Oct-2-Ene-2-Carboxylic Acid Sodium Salt; Sodium (6R,7R)-7-[(2-Amino-2-phenylacetyl)amino]-3-methylidene-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate; 3-Methylenephalosporanic Acid Derivative; D-α-Aminobenzylpenicillanic Acid Sodium Salt Derivative; β-Lactam Intermediate; Antibiotic Synthesis Intermediate
EINECS	Contact for details

Quality Control

Our [6R-[6α,7β(R*)]]-7-[(Aminophenylacetyl)Amino]-3-Methylene-8-Oxo-5-Thia-1-Azabicyclo[4.2.0]Octane-2-Carboxylic Acid Sodium Salt is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for pharmaceutical intermediate applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals (as Pb)	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.