Description

n-(tert-Butoxycarbonyl)Dopamine is a protected derivative of the neurotransmitter dopamine, where the primary amine is shielded by a tert-butoxycarbonyl (Boc) group. This chemical modification is critical for enabling selective synthetic transformations in complex organic and peptide synthesis, preventing unwanted side reactions. It is an essential building block for researchers and manufacturers in the pharmaceutical and life sciences sectors, particularly in the development of neuroactive compounds, prodrugs, and advanced chemical intermediates.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of dopamine receptor agonists, antagonists, and related neuropharmaceuticals.
• Peptide Synthesis: Serves as a Boc-protected amino acid derivative for the solid-phase and solution-phase synthesis of bioactive peptides.
• Chemical Research: Used in medicinal chemistry for structure-activity relationship (SAR) studies and the development of novel central nervous system (CNS) targeted compounds.
• Prodrug Development: Employed to create protected forms of dopamine designed for improved stability, bioavailability, and targeted delivery.
• Bioconjugation: Useful for attaching dopamine moieties to other molecules, polymers, or surfaces for diagnostic and material science applications.
• Reference Standard: Acts as a high-purity analytical standard for quality control and research in analytical laboratories.

Basic Information

Product Name	n-(tert-Butoxycarbonyl)Dopamine
CAS No.	37034-31-4
Molecular Formula	C₁₃H₁₉NO₄
Molecular Weight	253.29 g/mol
Synonyms	Boc-Dopamine; N-Boc-dopamine; 4-(2-Aminoethyl)-1,2-benzenediol, N-Boc derivative; 2-[(3,4-Dihydroxyphenyl)ethyl]carbamic acid 1,1-dimethylethyl ester; Dopamine N-Boc; tert-Butyl (2-(3,4-dihydroxyphenyl)ethyl)carbamate; N-(tert-Butoxycarbonyl)-3,4-dihydroxyphenethylamine
EINECS	Contact for details

Quality Control

Our n-(tert-Butoxycarbonyl)Dopamine is manufactured under strict quality management systems. Each batch is subjected to rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment supports applications in GMP and research environments where reliable purity and traceability are paramount.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.