Description

2-Amino-2-Cyclopropylpropanenitrile is a versatile chiral building block featuring both a nitrile and an amino functional group on a cyclopropane scaffold. This compound is of significant value in organic synthesis, particularly for the construction of complex molecules in pharmaceutical and agrochemical research. It serves as a key intermediate for medicinal chemists and process development scientists seeking to introduce cyclopropyl and amino-nitrile motifs into target structures.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for drugs targeting central nervous system (CNS) disorders and antiviral therapies.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the biological activity of the cyclopropane ring.
• Chiral Ligand & Catalyst Development: Serves as a starting material for synthesizing chiral auxiliaries, ligands for asymmetric catalysis, and organocatalysts.
• Fine Chemical Building Block: Employed in custom synthesis and research for creating complex, high-value specialty chemicals.
• Peptidomimetics Research: The amino-nitrile moiety is useful in the design and synthesis of peptide analogs and protease inhibitors.

Basic Information

Product Name	2-Amino-2-Cyclopropylpropanenitrile
CAS No.	37024-73-0
Molecular Formula	C7H12N2
Molecular Weight	124.19 g/mol
Synonyms	2-Cyclopropyl-2-aminopropanenitrile; α-Amino-α-cyclopropylpropionitrile; 2-Amino-2-cyclopropylpropionitrile; 2-Cyclopropylalaninenitrile; (Aminocyclopropyl)acetonitrile; 2-Cyclopropyl-2-aminopropiononitrile; α-Cyclopropyl-α-aminopropionitrile
EINECS	Contact for details

Quality Control

Our 2-Amino-2-Cyclopropylpropanenitrile is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, which includes results from HPLC, GC, NMR, and other relevant methods. Our quality commitment supports applications requiring high-purity intermediates for GMP and non-GMP synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if possible to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Optical Purity (Chiral HPLC)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.