Description

5-Iodoacetamidosalicylic Acid is a specialized chemical intermediate featuring a reactive iodoacetamide group on a salicylic acid backbone. This compound matters for its utility as a key building block in the synthesis of more complex molecules, particularly in pharmaceutical research and development. It is primarily needed by industries focused on creating novel active pharmaceutical ingredients (APIs), diagnostic agents, and biochemical probes, where its structure enables targeted modifications.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of potential drug candidates, especially those targeting specific enzymes or receptors.
• Bioconjugation Reagent: Used to modify proteins, peptides, or antibodies by selectively alkylating cysteine residues via its iodoacetamide moiety.
• Proteomics Research: Employed in the development of activity-based probes (ABPs) for studying enzyme function and inhibition.
• Diagnostic Agent Synthesis: Serves as a starting material for creating contrast agents or labeled compounds used in medical imaging.
• Chemical Biology Tool: Utilized to create affinity tags or cross-linking agents for studying biomolecular interactions.
• Organic Synthesis Building Block: Used in academic and industrial R&D for constructing complex heterocyclic or functionalized aromatic compounds.

Basic Information

Product Name	5-Iodoacetamidosalicylic Acid
CAS No.	36930-65-1
Molecular Formula	C9H8INO4
Molecular Weight	321.07 g/mol
Synonyms	5-(Iodoacetamido)salicylic Acid; 2-Hydroxy-5-(iodoacetamido)benzoic Acid; N-(2-Hydroxy-5-carboxyphenyl)iodoacetamide; 5-IA-SA; Iodoacetamidosalicylic Acid; 5-Iodoacetamido-2-hydroxybenzoic Acid; 5-(2-Iodoacetamido)salicylic Acid; 5-IAS
EINECS	Contact for details

Quality Control

Our 5-Iodoacetamidosalicylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for research and pharmaceutical intermediate applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed in a dry environment to prevent degradation. For long-term storage, consider using a desiccant.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%
Single Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.