Description

1-Oxaspiro[2.5]octane-2-carbonitrile is a versatile spirocyclic nitrile compound that serves as a valuable synthetic intermediate in advanced organic chemistry. Its unique bridged structure makes it a critical building block for constructing complex molecular architectures, particularly in pharmaceutical research and development. This high-purity intermediate is essential for medicinal chemists and process R&D teams in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Agrochemical Synthesis: Used in the development of new-generation pesticides and herbicides with spirocyclic motifs for enhanced efficacy.
• Ligand and Catalyst Development: Serves as a scaffold for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of specialty polymers and advanced organic materials with specific functional properties.
• Academic & Process Chemistry: A valuable reagent for methodology development and studying spirocyclic ring formation reactions in university and industrial R&D labs.

Basic Information

Product Name	1-Oxaspiro[2.5]octane-2-carbonitrile
CAS No.	36929-66-5
Molecular Formula	C8H11NO
Molecular Weight	137.18 g/mol
Synonyms	1-Oxaspiro[2.5]octane-2-carbonitrile; 2-Cyano-1-oxaspiro[2.5]octane; 1-Oxaspiro(2.5)octane-2-carbonitrile; Spiro[cyclopropane-1,2'-[1,4]oxazepane]-3'-carbonitrile; Oxaspirooctanecarbonitrile
EINECS	Contact for details

Quality Control

Our 1-Oxaspiro[2.5]octane-2-carbonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment, confirming compliance with customer specifications and internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider maintaining under an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.