Description

Methyl Pentafluorophenyl Carbonate is a specialized fluorinated organic carbonate ester. This compound serves as a versatile and highly reactive intermediate in advanced organic synthesis, particularly for the introduction of the pentafluorophenyloxycarbonyl protecting group. It is primarily utilized by research institutions and industrial R&D departments focused on developing pharmaceuticals, agrochemicals, and high-performance materials where precise molecular modification is critical.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), especially for carbamate prodrugs and protecting group chemistry.
• Peptide Synthesis: Used as a coupling agent or for introducing the pentafluorophenyl (Pfp) ester group in solid-phase and solution-phase peptide synthesis.
• Agrochemical Research: Intermediate in the development of novel herbicides, fungicides, and insecticides with fluorinated motifs for enhanced activity and stability.
• Polymer Chemistry: Monomer or modifying agent for creating specialty fluorinated polymers with unique surface properties and chemical resistance.
• Material Science: Precursor for surface functionalization and the creation of advanced coatings and composites.
• Chemical Biology Probes: Useful for labeling and modifying biomolecules in research applications due to its high reactivity.

Basic Information

Product Name	Methyl Pentafluorophenyl Carbonate
CAS No.	36919-03-6
Molecular Formula	C8H3F5O3
Molecular Weight	242.10 g/mol
Synonyms	Methyl Pentafluorophenyl Carbonate; Methyl Perfluorophenyl Carbonate; Pentafluorophenyl Methyl Carbonate; Carbonochloridic Acid, Pentafluorophenyl Methyl Ester; Methyl Carbonochloridate, Pentafluorophenyl Ester; MFPC; 2,3,4,5,6-Pentafluorophenyl Methyl Carbonate
EINECS	Contact for details

Quality Control

Our Methyl Pentafluorophenyl Carbonate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong bases and fluorides. Handle and store under an inert atmosphere if prolonged storage is required.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.