Description

2-[3-(Trifluoromethyl)Phenoxy]Nicotinic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its distinct trifluoromethylphenoxy and nicotinic acid structure. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted bioactivity. It is an essential building block for research and development chemists and manufacturers in the global pharmaceutical and agrochemical industries.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of advanced herbicides and pesticides, leveraging the trifluoromethyl group for enhanced efficacy.
• Chemical Research: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Material Science: Potential use in the development of specialty polymers and liquid crystals due to its aromatic and fluorinated components.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	2-[3-(Trifluoromethyl)Phenoxy]Nicotinic Acid
CAS No.	36701-89-0
Molecular Formula	C13H8F3NO3
Molecular Weight	283.21 g/mol
Synonyms	2-[[3-(Trifluoromethyl)phenoxy]pyridine-3-carboxylic acid; Nicotinic acid, 2-[3-(trifluoromethyl)phenoxy]-; 2-(3-Trifluoromethylphenoxy)nicotinic acid; 2-(α,α,α-Trifluoro-m-tolyloxy)nicotinic acid; 3-Pyridinecarboxylic acid, 2-[3-(trifluoromethyl)phenoxy]-
EINECS	Contact for details

Quality Control

Every batch of 2-[3-(Trifluoromethyl)Phenoxy]Nicotinic Acid is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency meet the high standards required for pharmaceutical development. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.