Description

(+/-)-Butaclamol Hcl CAS NO 36504-94-6 is a potent, non-selective dopamine receptor antagonist belonging to the class of dibenzocycloheptapyridines. This compound is of significant value in neuroscience research and pharmaceutical development as a key reference standard and pharmacological tool. It is primarily required by research institutions, pharmaceutical R&D departments, and analytical laboratories engaged in neuropharmacology, receptor binding studies, and the development of central nervous system (CNS) therapeutics.

Application

• Pharmacological Research: Used as a standard dopamine D1 and D2 receptor antagonist in receptor binding assays and functional studies.
• Neuroscience Studies: A critical tool for investigating dopaminergic pathways, neurotransmission, and behaviors related to psychosis and movement disorders.
• Reference Standard: Serves as a high-purity certified reference material (CRM) for analytical method development, validation, and quality control in pharmaceutical analysis.
• Drug Discovery: Employed in high-throughput screening (HTS) and structure-activity relationship (SAR) studies for novel antipsychotic and neuroleptic agents.
• Academic Research: Utilized in university and institutional labs for teaching and advanced research into neuropsychiatric conditions.
• Biochemical Assays: Acts as a ligand in competitive binding experiments to characterize receptor subtypes and affinities.

Basic Information

Product Name	(+/-)-Butaclamol Hydrochloride
CAS No.	36504-94-6
Molecular Formula	C25H31NO • HCl
Molecular Weight	397.98 g/mol
Synonyms	Butaclamol Hydrochloride; (±)-Butaclamol Hydrochloride; Butaclamol HCl; 3,4,5,6,7,8,9,10-Octahydro-6,11-dimethyl-3-(1-methyl-3-phenylpropyl)-2,6-methano-1H-3-benzazocin-1-ol Hydrochloride; AY-23,028; NSC 339024; 1H-3-Benzazocin-1-ol, 3,4,5,6,7,8,9,10-octahydro-6,11-dimethyl-3-(1-methyl-3-phenylpropyl)-2,6-methano-, hydrochloride, (±)-
EINECS	Contact for details

Quality Control

Our (+/-)-Butaclamol HCl is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, identity confirmation by IR and NMR spectroscopy, and residual solvent analysis, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, cool place. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.