Description

Fibrinopeptide B CAS NO 36204-23-6 is a specific peptide fragment released from the beta chain of fibrinogen during its enzymatic conversion to fibrin by thrombin. This compound is of significant value in biochemical and medical research for studying blood coagulation mechanisms and related disorders. It serves as a critical reagent for researchers and diagnostic manufacturers focused on hemostasis, thrombosis, and the development of assays for coagulation factor activity.

Application

• Biochemical Research: Used as a standard or substrate in studies investigating the kinetics and specificity of thrombin and other coagulation-related enzymes.
• Diagnostic Assay Development: Essential for the calibration and validation of in-vitro diagnostic (IVD) tests designed to measure fibrinopeptide release, thrombin activity, or fibrinogen functionality.
• Pharmaceutical R&D: Employed in drug discovery programs targeting the coagulation cascade, aiding in the screening and evaluation of potential antithrombotic or pro-coagulant compounds.
• Clinical Studies: Acts as a biomarker in research studies analyzing fibrin formation rates and abnormalities in patient plasma samples.
• Quality Control: Serves as a reference material for the quality assurance of therapeutic proteins derived from blood plasma.

Basic Information

Product Name	Fibrinopeptide B
CAS No.	36204-23-6
Molecular Formula	C47H69N13O15S
Molecular Weight	1080.2 g/mol
Synonyms	Fibrinopeptide B (Human); FpB; Fibrinogen Beta Chain (43-63); H-Gly-Val-Asn-Asp-Asn-Glu-Glu-Gly-Phe-Phe-Ser-Ala-Arg-OH; Human Fibrinopeptide B; Thrombin Peptide B; FPB (1-14); Fibrin I Peptide B
EINECS	Contact for details

Quality Control

Our Fibrinopeptide B is produced under stringent conditions to ensure high purity and batch-to-batch consistency, suitable for sensitive research and diagnostic applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and other critical parameters. We adhere to relevant quality management standards to support our global clientele in regulated environments.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, keep desiccated. Allow the vial to reach room temperature in a dry environment before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Water Content (KF)	≤ 5.0%
Solubility	Soluble in water, dilute acetic acid

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.