Description

1-[3,5-Bis(Trifluoromethyl)Phenyl]Biguanide Hydrochloride is a specialized organic compound featuring a biguanide pharmacophore linked to a highly fluorinated aromatic ring system. This unique structure makes it a valuable high-purity intermediate in advanced pharmaceutical and agrochemical synthesis. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical industry for the development of novel therapeutic agents, particularly those targeting metabolic and infectious diseases.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly for antiviral, antidiabetic, and antimicrobial applications.
• Agrochemical Research: Used in the development of advanced pesticides and herbicides, where the trifluoromethyl groups enhance biological activity and environmental stability.
• Chemical Biology Probe: Serves as a precursor for creating molecular probes to study biological pathways involving biguanide targets, such as mitochondrial complex I.
• Material Science Research: Potential monomer or additive for creating specialty polymers with unique surface properties or fluorine-containing functional materials.

Basic Information

Product Name	1-[3,5-Bis(Trifluoromethyl)Phenyl]Biguanide Hydrochloride
CAS No.	36068-40-3
Molecular Formula	C10H9ClF6N5
Molecular Weight	348.66 g/mol
Synonyms	N-(3,5-Bis(trifluoromethyl)phenyl)imidodicarbonimidic diamide hydrochloride; 1-(3,5-Bis(trifluoromethyl)phenyl)biguanide HCl; 3,5-Bis(trifluoromethyl)phenylbiguanide hydrochloride; Biguanide, 1-[3,5-bis(trifluoromethyl)phenyl]-, monohydrochloride; N1-(3,5-Bis(trifluoromethyl)phenyl)biguanide hydrochloride
EINECS	Contact for details

Quality Control

Our 1-[3,5-Bis(Trifluoromethyl)Phenyl]Biguanide Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the exacting standards required for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting purity, assay, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); the container must be kept tightly sealed and protected from humidity to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.