Description

[Bis(Trimethylsilyl)Methyl]Triphenylphosphonium Bromide is a highly versatile and reactive organosilicon phosphonium salt, serving as a critical reagent in advanced organic synthesis. Its primary value lies in its ability to act as a stabilized ylide precursor for the synthesis of vinylsilanes and other complex silicon-containing molecules, which are pivotal building blocks in materials science and pharmaceutical chemistry. This compound is essential for R&D chemists and process development scientists in the fine chemical, agrochemical, and advanced materials sectors, where precise carbon-silicon bond formation is required.

Application

• Wittig Olefination Reagent: Key precursor for generating stabilized ylides used in the stereoselective synthesis of vinylsilanes.
• Advanced Materials Synthesis: Building block for silicon-based polymers, liquid crystals, and organic semiconductors.
• Pharmaceutical Intermediates: Used in the synthesis of novel drug candidates, particularly those incorporating organosilicon pharmacophores.
• Agrochemical Development: Employed in creating silicon-modified active ingredients for crop protection agents.
• Cross-Coupling Reactions: Can serve as an organosilicon transfer agent in palladium-catalyzed coupling processes.
• Academic & Industrial R&D: A valuable tool for methodology development in organometallic and synthetic organic chemistry laboratories.

Basic Information

Product Name	[Bis(Trimethylsilyl)Methyl]Triphenylphosphonium Bromide
CAS No.	36050-79-0
Molecular Formula	C25H40BrPSi2
Molecular Weight	507.62 g/mol
Synonyms	(Bis(trimethylsilyl)methyl)triphenylphosphonium bromide; (Trimethylsilylmethyl)triphenylphosphonium bromide (bis-TMS derivative); Triphenyl[(trimethylsilyl)methyl]phosphonium bromide (bis-silylated); Phosphonium, [(trimethylsilyl)methyl]triphenyl-, bromide (1:1); TMS-methyl triphenylphosphonium bromide (bis-TMS); (TMS)2CHPPh3Br; BTMSTPPB; Silicon-stabilized Wittig reagent
EINECS	Contact for details

Quality Control

Our [Bis(Trimethylsilyl)Methyl]Triphenylphosphonium Bromide is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including NMR, HPLC, and elemental analysis, to ensure high purity and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support cGMP and ISO 9001 standards for reliable sourcing in regulated development environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.