Description

4,4,4-Trifluoro-1-(4-Nitrophenyl)Butane-1,3-Dione is a specialized fluorinated diketone building block of significant interest in advanced organic synthesis. This compound matters for its unique trifluoromethyl and nitro-substituted aromatic structure, which imparts valuable electronic and steric properties to target molecules. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine atoms enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for β-diketone ligands used in coordination chemistry and catalysis for asymmetric synthesis.
• Material Science Research: Employed in the synthesis of fluorinated organic semiconductors, liquid crystals, and other functional polymers.
• Chemical Research: A versatile building block for heterocyclic chemistry, enabling the construction of complex fluorinated pyrazoles, isoxazoles, and other ring systems.

Basic Information

Product Name	4,4,4-Trifluoro-1-(4-Nitrophenyl)Butane-1,3-Dione
CAS No.	35999-53-2
Molecular Formula	C10H6F3NO4
Molecular Weight	261.16 g/mol
Synonyms	1-(4-Nitrophenyl)-4,4,4-trifluorobutane-1,3-dione; 4,4,4-Trifluoro-1-(p-nitrophenyl)-1,3-butanedione; 4-Nitrophenyl trifluoroacetylacetone; p-Nitrophenyl trifluoroacetylacetone; 4,4,4-Trifluoro-1-(4-nitrophenyl)-1,3-butanedione; TFNBA; 4'-Nitro-2,4,4-trifluoroacetylacetophenone
EINECS	Contact for details

Quality Control

Our 4,4,4-Trifluoro-1-(4-Nitrophenyl)Butane-1,3-Dione is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and scale-up applications. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.