Description

Acetamide, 2,2,2-Trifluoro-n-(4-Fluorophenyl)- is a specialized fluorinated acetamide derivative with the CAS number 35980-25-7. This compound is a high-value intermediate prized for its unique chemical structure, which incorporates both trifluoromethyl and fluorophenyl groups, making it a versatile building block in advanced synthesis. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for molecules targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the fluorine atoms enhance biological activity, stability, and selectivity.
• Material Science Research: Serves as a precursor for developing specialty polymers, liquid crystals, or organic electronic materials with tailored properties.
• Fluorine Chemistry Building Block: Essential for medicinal and synthetic chemists exploring structure-activity relationships (SAR) by introducing fluorinated motifs.
• Contract Research & Manufacturing (CRAM): Supplied to custom synthesis organizations for scale-up and process development of client-specific molecules.
• Academic Research: Utilized in university and institutional labs for methodological studies in organic synthesis and fluorine chemistry.

Basic Information

Product Name	Acetamide, 2,2,2-Trifluoro-n-(4-Fluorophenyl)-
CAS No.	35980-25-7
Molecular Formula	C9H7F4NO
Molecular Weight	221.15 g/mol
Synonyms	2,2,2-Trifluoro-N-(4-fluorophenyl)acetamide; N-(4-Fluorophenyl)-2,2,2-trifluoroacetamide; 4-Fluorophenyltrifluoroacetamide; α,α,α-Trifluoro-p-fluoroacetanilide; p-Fluoro-α,α,α-trifluoroacetanilide; TFAA-4F; TFA-4F Anilide
EINECS	Contact for details

Quality Control

Every batch of Acetamide, 2,2,2-Trifluoro-n-(4-Fluorophenyl)- is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the precise requirements for research and scale-up. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming identity, purity, and impurity profiles as determined by HPLC, GC, NMR, and IR spectroscopy.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.