Description

Formamide-N,n-D2 is a deuterated derivative of formamide, where the two hydrogen atoms on the nitrogen are replaced with deuterium atoms (CAS NO 35645-04-6). This isotopic labeling makes it a crucial reagent in advanced research fields such as nuclear magnetic resonance (NMR) spectroscopy and reaction mechanism studies, where it serves as a non-radioactive tracer. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and specialty chemical manufacturers focused on developing deuterated active pharmaceutical ingredients (APIs) and other labeled compounds.

Application

• NMR Spectroscopy Solvent & Standard: Used as a deuterated solvent and internal standard for high-resolution NMR analysis in organic chemistry and structural biology.
• Deuterium Labeling Reagent: Serves as a source of deuterium atoms in the synthesis of deuterium-labeled compounds for metabolic, pharmacokinetic, and stability studies.
• Pharmaceutical Research: Employed in the development and production of deuterated drugs, where the incorporation of deuterium can alter metabolic pathways and improve drug profiles.
• Mechanistic Studies: Acts as a probe in chemical reaction kinetics and mechanism elucidation due to its isotopic mass difference.
• Polymer & Material Science: Used in the synthesis of specialty polymers and materials where deuterium labeling is required for analytical characterization techniques like neutron scattering.
• Analytical Chemistry: Functions as a component in mobile phases or matrices for advanced mass spectrometry (MS) and chromatography applications.

Basic Information

Product Name	Formamide-N,n-D2
CAS No.	35645-04-6
Molecular Formula	DCOND2
Molecular Weight	47.06 g/mol
Synonyms	N,N-Dideuteroformamide; Deuterated Formamide; Formamide-d2; [N,N-2H2]Formamide; N,N-Dideuterioformamide; Dideuteroformamide; Formic acid amide-d2; Amid-d2
EINECS	Contact for details

Quality Control

Our Formamide-N,n-D2 is produced under stringent conditions to ensure high isotopic purity and chemical integrity. Each batch undergoes rigorous quality testing, including analysis by NMR, GC, and Karl Fischer titration, to confirm deuterium enrichment, chemical purity, and moisture content. Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent absorption of atmospheric moisture, which can affect isotopic purity and stability.

Specification

Item	Specification
Appearance	Clear, colorless liquid
Identification (IR)	Conforms to structure
Deuterium Content (NMR)	≥ 98 atom % D
Assay (GC)	≥ 99.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.