Description

2-Amino-4-(Trifluoromethyl)Oxazole is a high-value heterocyclic building block characterized by its oxazole core and trifluoromethyl substituent. This compound matters for its role as a critical intermediate in the synthesis of advanced pharmaceuticals and agrochemicals, where the CF₃ group is prized for enhancing metabolic stability and lipophilicity. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in antiviral, antibacterial, and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the trifluoromethyl group improves biological activity.
• Material Science Research: Serves as a building block for novel organic electronic materials and liquid crystals.
• Chemical Biology & Proteomics: Employed as a versatile scaffold for designing enzyme inhibitors and molecular probes.
• Custom Synthesis & Contract Manufacturing: A crucial starting material for custom synthesis projects and scale-up services for clients in life sciences.

Basic Information

Product Name	2-Amino-4-(Trifluoromethyl)Oxazole
CAS No.	35629-71-1
Molecular Formula	C₄H₃F₃N₂O
Molecular Weight	152.08 g/mol
Synonyms	4-(Trifluoromethyl)-1,3-oxazol-2-amine; 2-Amino-4-trifluoromethyloxazole; 4-(Trifluoromethyl)-2-oxazolamine; 2-Amino-4-(trifluoromethyl)-1,3-oxazole; Oxazole, 2-amino-4-(trifluoromethyl)-; 2-Amino-α,α,α-trifluoro-4-oxazolemethanol (tautomer); 35629-71-1
EINECS	Contact for details

Quality Control

Our 2-Amino-4-(Trifluoromethyl)Oxazole is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical parameters. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). The compound is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.