Description

(20ξ)-7,8β-Dihydro-3-o-Methylbatrachotoxinin A is a highly specialized, semi-synthetic derivative of the potent neurotoxic alkaloid batrachotoxin. This compound is of significant interest in advanced pharmacological and neurobiological research due to its interaction with voltage-gated sodium channels. It serves as a critical reference standard and research tool for scientists in the fields of toxicology, neuroscience, and drug discovery, enabling the study of ion channel function and the development of novel therapeutic agents.

Application

• Neuroscience Research: As a key pharmacological tool for studying the modulation and block of voltage-gated sodium channels in neuronal signaling.
• Toxicology & Pharmacology: Used as a reference standard in the investigation of neurotoxins and the mechanisms of action of channel-targeting compounds.
• Drug Discovery: Employed in high-throughput screening assays to identify potential antidotes or novel therapeutic agents that interact with sodium channels.
• Biochemical Research: Utilized in structure-activity relationship (SAR) studies to understand the chemical basis of batrachotoxin's potency and selectivity.
• Analytical Standard: Serves as a certified reference material (CRM) for the qualitative and quantitative analysis of related steroidal alkaloids in complex matrices.

Basic Information

Product Name	(20ξ)-7,8β-Dihydro-3-o-Methylbatrachotoxinin A
CAS No.	35596-59-9
Molecular Formula	C32H45NO6
Molecular Weight	539.71 g/mol
Synonyms	3-O-Methylbatrachotoxinin A, 7,8-Dihydro Derivative; 20-Epi-7,8-dihydro-3-O-methylbatrachotoxinin A; 3-O-Methyl-7,8-dihydrobatrachotoxinin A; Batrachotoxinin A, 3-O-methyl-, 7,8-dihydro-; (20ξ)-7,8β-Dihydro-3-O-methylbatrachotoxinin A; 3-Methoxy-7,8-dihydrobatrachotoxinin A
EINECS	Contact for details

Quality Control

Every batch of (20ξ)-7,8β-Dihydro-3-o-Methylbatrachotoxinin A is produced and analyzed under strict quality management protocols to ensure identity, purity, and consistency. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, detailing comprehensive analytical results from techniques including HPLC, NMR, and mass spectrometry.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This light-sensitive material should be handled and stored to minimize prolonged exposure to light and moisture to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.