Description

(6R-Cis)-3-(Acetoxymethyl)-7-Methoxy-8-Oxo-7-(2-Thienylacetamido)-5-Thia-1-Azabicyclo[4.2.0]Oct-2-Ene-2-Carboxylic Acid CAS NO 35565-06-1 is a high-purity, advanced pharmaceutical intermediate belonging to the cephalosporin class of β-lactam antibiotics. This compound is critical for the synthesis of next-generation antibiotics, offering a reliable and scalable building block for complex drug manufacturing. It is primarily required by pharmaceutical R&D laboratories, API (Active Pharmaceutical Ingredient) manufacturers, and fine chemical synthesis facilities focused on anti-infective therapies.

Application

• Key Intermediate in Cephalosporin Antibiotic Synthesis: Serves as a crucial precursor in the production of advanced cephalosporin-based APIs.
• Pharmaceutical Research & Development: Used in medicinal chemistry for the discovery and optimization of new antibacterial agents.
• Process Chemistry & Scale-Up: Employed in developing and optimizing robust, cost-effective manufacturing routes for final drug substances.
• Reference Standard: Functions as a high-purity analytical standard for quality control and regulatory submissions.
• Custom Synthesis: A starting material for the preparation of novel cephalosporin derivatives with modified therapeutic profiles.

Basic Information

Product Name	(6R-Cis)-3-(Acetoxymethyl)-7-Methoxy-8-Oxo-7-(2-Thienylacetamido)-5-Thia-1-Azabicyclo[4.2.0]Oct-2-Ene-2-Carboxylic Acid
CAS No.	35565-06-1
Molecular Formula	C18H19N3O7S2
Molecular Weight	453.49 g/mol
Synonyms	7-Methoxy-3-[(acetyloxy)methyl]-8-oxo-7-[2-(2-thienyl)acetamido]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid; Cefoxitin Intermediate; Cefoxitin Sodium Intermediate; 3-Acetoxymethyl-7-methoxy-8-oxo-7-[2-(thiophen-2-yl)acetamido]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid; (6R,7S)-3-(Acetoxymethyl)-7-methoxy-8-oxo-7-(2-thienylacetamido)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid; SQ 14,359 Free Acid; Antibiotic SQ 14,359
EINECS	Contact for details

Quality Control

Our (6R-Cis)-3-(Acetoxymethyl)-7-Methoxy-8-Oxo-7-(2-Thienylacetamido)-5-Thia-1-Azabicyclo[4.2.0]Oct-2-Ene-2-Carboxylic Acid is manufactured under strict quality systems suitable for pharmaceutical applications. Products undergo rigorous analytical testing including HPLC, NMR, and MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) is provided with each batch, detailing all specifications and test results.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.