Description

1-(4-Nitrophenyl)-4,4,4-Trifluoro-3-Trifluoromethyl-2-Buten-1-One is a specialized fluorinated organic building block characterized by a unique combination of a nitrophenyl group and a highly fluorinated butenone moiety. This compound is valued for its role as a key intermediate in the synthesis of advanced materials and active pharmaceutical ingredients (APIs), where its specific fluorine substitution pattern is critical. It is primarily sought by research and development teams in the pharmaceutical, agrochemical, and advanced material science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a crucial synthon in the research and development of novel drug candidates, particularly those requiring fluorinated scaffolds for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the fluorine atoms contribute to improved efficacy and environmental persistence.
• Advanced Material Precursor: Acts as a building block for fluorinated polymers, liquid crystals, and other specialty materials that demand specific electronic and surface properties.
• Organic Synthesis Research: Employed in academic and industrial R&D laboratories for exploring new fluorination methodologies and constructing complex organic molecules.
• Chemical Intermediate for Dyes and Pigments: The nitrophenyl group makes it a potential intermediate in the synthesis of specialized dyes and colorants.

Basic Information

Item	Details
Product Name	1-(4-Nitrophenyl)-4,4,4-Trifluoro-3-Trifluoromethyl-2-Buten-1-One
CAS No.	35443-90-4
Molecular Formula	C11H5F6NO3
Molecular Weight	313.16 g/mol
Synonyms	4,4,4-Trifluoro-3-(trifluoromethyl)-1-(4-nitrophenyl)-2-buten-1-one; 1-(4-Nitrophenyl)-4,4,4-trifluoro-3-(trifluoromethyl)-2-buten-1-one; 4-Nitrobenzoyltrifluoroacetone; 4,4,4-Trifluoro-1-(4-nitrophenyl)-3-(trifluoromethyl)-2-buten-1-one; (E)-4,4,4-Trifluoro-1-(4-nitrophenyl)-3-(trifluoromethyl)but-2-en-1-one; 35443-90-4; 1-(p-Nitrophenyl)-4,4,4-trifluoro-3-trifluoromethyl-2-buten-1-one
EINECS	Contact for details

Quality Control

Our 1-(4-Nitrophenyl)-4,4,4-Trifluoro-3-Trifluoromethyl-2-Buten-1-One is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and storage should minimize exposure to direct light.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.