Description

B-Amino-4-Fluorobenzenepropanol CAS NO 35373-69-4 is a high-purity fluorinated aromatic amino alcohol building block of significant importance in advanced organic synthesis. Its molecular structure, featuring both an amino group and a fluorinated benzene ring, makes it a versatile intermediate for constructing complex pharmacologically active molecules. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral building block in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and cardiovascular therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced fluorinated pesticides and herbicides, where the fluorine atom enhances biological activity and stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated compounds used in electronic display technologies due to its aromatic and polar properties.
• Peptidomimetics & Bio-conjugation: The amino and hydroxyl functional groups allow for its incorporation into peptide analogs and linker molecules for bioconjugation applications.
• Asymmetric Catalyst Ligand Synthesis: Utilized in the preparation of chiral ligands for asymmetric catalysis, crucial for producing enantiomerically pure compounds.
• Polymer Modification: Acts as a monomer or cross-linking agent for introducing fluorine and amine functionality into specialty polymers, improving their surface and thermal properties.

Basic Information

Product Name	B-Amino-4-Fluorobenzenepropanol
CAS No.	35373-69-4
Molecular Formula	C9H12FNO
Molecular Weight	169.20 g/mol
Synonyms	4-Fluoro-β-aminohydrocinnamyl alcohol; 3-Amino-1-(4-fluorophenyl)propan-1-ol; 1-(4-Fluorophenyl)-3-aminopropan-1-ol; 4-Fluoro-β-aminophenethyl alcohol; B-Amino-4-fluorohydrocinnamyl alcohol; (RS)-3-Amino-1-(4-fluorophenyl)propan-1-ol; (±)-3-Amino-1-(4-fluorophenyl)-1-propanol
EINECS	Contact for details

Quality Control

Our B-Amino-4-Fluorobenzenepropanol is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for demanding research and scale-up processes. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP guidelines where applicable, ensuring the material meets the stringent requirements for pharmaceutical intermediate use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen) after opening to prevent degradation and absorption of moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.