Description

1-n-Boc-Aminocyclopentanecarboxylic Acid is a high-purity, protected amino acid derivative essential for advanced organic synthesis. This compound serves as a critical building block for the construction of complex molecules, offering precise control over stereochemistry and functional group compatibility. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutics, including peptide mimetics and small molecule drug candidates.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates.
• Peptidomimetic Chemistry: Used to introduce constrained cyclopentane scaffolds into peptide backbones to enhance metabolic stability and bioavailability.
• Protease Inhibitor Development: Serves as a core structure for designing inhibitors targeting various protease enzymes.
• Combinatorial Chemistry: Employed in solid-phase and solution-phase parallel synthesis for generating diverse compound libraries.
• Bioconjugation: The carboxylic acid and Boc-protected amine functionalities allow for selective conjugation to other molecules or surfaces.
• Academic & Industrial Research: Fundamental research tool in medicinal chemistry and chemical biology for exploring structure-activity relationships (SAR).

Basic Information

Product Name	1-n-Boc-Aminocyclopentanecarboxylic Acid
CAS No.	35264-09-6
Molecular Formula	C11H19NO4
Molecular Weight	229.27 g/mol
Synonyms	1-[(tert-Butoxycarbonyl)amino]cyclopentanecarboxylic Acid; (1-((tert-Butoxycarbonyl)amino)cyclopentyl)carboxylic Acid; Boc-ACPC-OH; Boc-1-Aminocyclopentanecarboxylic Acid; 1-(Boc-amino)cyclopentanecarboxylic Acid; Cyclopentanecarboxylic acid, 1-[(1,1-dimethylethoxy)carbonyl]amino]-; 1-Aminocyclopentanecarboxylic acid, N-Boc-; tert-Butyl 1-carboxycyclopentylcarbamate
EINECS	Contact for details

Quality Control

Our 1-n-Boc-Aminocyclopentanecarboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and structural integrity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. Keep away from strong acids and organic solvents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥98.0%
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.