Description

tert-Butoxycarbonylamino-Cyclohexyl-Acetic Acid CAS NO 35264-05-2 is a protected amino acid derivative featuring a cyclohexyl backbone and a Boc-protected amine group. This compound is a crucial chiral building block in the synthesis of complex pharmaceutical intermediates and active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for developing novel therapeutic agents and specialty chemicals.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the production of peptide-based drugs, enzyme inhibitors, and other bioactive molecules.
• API Synthesis: Used in the multi-step synthesis of complex target molecules requiring a protected cyclohexylglycine moiety.
• Peptidomimetics Research: Serves as a critical scaffold in medicinal chemistry for designing and synthesizing peptide analogs with enhanced metabolic stability.
• Agrochemical Development: Employed in the research and synthesis of advanced herbicides and fungicides with specific stereochemical requirements.
• Asymmetric Synthesis: Valuable starting material or auxiliary in catalytic asymmetric reactions to introduce chiral centers.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of client-specific intermediates under cGMP conditions.

Basic Information

Product Name	tert-Butoxycarbonylamino-Cyclohexyl-Acetic Acid
CAS No.	35264-05-2
Molecular Formula	C₁₃H₂₃NO₄
Molecular Weight	257.33 g/mol
Synonyms	Boc-Cyclohexylglycine; (1-(((tert-Butoxy)carbonyl)amino)cyclohexyl)acetic Acid; N-Boc-1-Aminocyclohexane-1-acetic Acid; N-(tert-Butoxycarbonyl)-1-aminocyclohexaneacetic Acid; 2-[(tert-Butoxycarbonyl)amino]-2-cyclohexylacetic Acid; Boc-NH-CH(C₆H₁₁)-COOH; BOC-Cyg-OH; 35264-05-2
EINECS	Contact for details

Quality Control

Our tert-Butoxycarbonylamino-Cyclohexyl-Acetic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis, to ensure it meets the high standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation. Keep away from strong acids and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm
Single Unknown Impurity (HPLC)	≤0.5%
Total Impurities (HPLC)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.