Description

3-(o-Chlorophenyl)-3-Hydroxy-3-Phenylpropiononitrile is a specialized organic intermediate featuring a nitrile and a tertiary alcohol functional group on a diphenylmethane backbone. This compound matters as a versatile chiral building block for the synthesis of complex molecules, particularly in the pharmaceutical sector. It is primarily needed by research and development chemists and process engineers in the fine chemical and pharmaceutical industries for creating active pharmaceutical ingredients (APIs) and other high-value compounds.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of various drug candidates and active pharmaceutical ingredients (APIs).
• Agrochemical Research: Used in the development of novel pesticides and herbicides, leveraging its structural complexity.
• Material Science: Potential monomer or precursor for specialty polymers and advanced organic materials.
• Academic & Industrial R&D: Serves as a valuable substrate for methodological development in organic synthesis and catalysis studies.
• Fine Chemical Synthesis: Employed in the multi-step production of complex fragrance and flavor molecules.

Basic Information

Product Name	3-(o-Chlorophenyl)-3-Hydroxy-3-Phenylpropiononitrile
CAS No.	35173-29-6
Molecular Formula	C15H12ClNO
Molecular Weight	257.71 g/mol
Synonyms	2-Chloro-α-(cyanomethyl)benzhydrol; α-(2-Chlorophenyl)-α-phenyl-β-hydroxypropionitrile; 3-Hydroxy-3-(2-chlorophenyl)-3-phenylpropanenitrile; Benzhydrol, 2-chloro-α-(cyanomethyl)-; (RS)-3-(2-Chlorophenyl)-3-hydroxy-3-phenylpropionitrile; 3-(2-Chlorophenyl)-3-hydroxy-3-phenylpropiononitrile
EINECS	Contact for details

Quality Control

Our 3-(o-Chlorophenyl)-3-Hydroxy-3-Phenylpropiononitrile is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and synthesis applications. Certificates of Analysis (COA) documenting all critical parameters are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.