Description

4-[(1-Adamantylcarbonyl)Amino]Butanoic Acid is a high-purity, functionalized adamantane derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, combining the rigid, lipophilic adamantane moiety with a carboxylic acid linker, makes it invaluable for creating novel compounds with tailored properties. This intermediate is primarily sought by research and development teams in the pharmaceutical and specialty chemical industries for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders or requiring enhanced bioavailability.
• Medicinal Chemistry Research: Used in the design and development of new drug candidates, leveraging the adamantane group for its metabolic stability and ability to penetrate lipid membranes.
• Peptidomimetics & Bio-Conjugation: The carboxylic acid functionality allows for coupling reactions to create peptide analogs or for linking pharmacophores to carriers, antibodies, or other biomolecules.
• Material Science Precursor: Serves as a monomer or modifier in the synthesis of advanced polymers, dendrimers, or supramolecular structures with unique thermal or mechanical properties.
• Ligand & Catalyst Development: Utilized to create sophisticated ligands for catalysis or metal-organic frameworks (MOFs), where the adamantyl group can impart steric bulk and influence geometry.
• Chemical Biology Probes: Acts as a scaffold for developing molecular probes and diagnostic agents used in biochemical and cellular research.

Basic Information

Product Name	4-[(1-Adamantylcarbonyl)Amino]Butanoic Acid
CAS No.	35091-21-5
Molecular Formula	C15H23NO3
Molecular Weight	265.35 g/mol
Synonyms	4-[(Adamantane-1-carbonyl)amino]butanoic acid; N-(1-Adamantylcarbonyl)-4-aminobutyric acid; 4-(1-Adamantanecarboxamido)butyric acid; 4-(Adamantane-1-carboxamido)butanoic acid; γ-(1-Adamantanecarboxamido)butyric acid; Adiphenine impurity; Adamantane-1-carboxylic acid (4-carboxybutyl)amide
EINECS	Contact for details

Quality Control

Every batch of 4-[(1-Adamantylcarbonyl)Amino]Butanoic Acid is manufactured under a strict quality management system and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, detailing key parameters such as assay, impurity profile, and residual solvents. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect stability and handling properties. For long-term storage, consider the use of a desiccant.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.