Description

1-Chloro-5-Dodecyne is a specialized aliphatic building block featuring both a terminal chloro and a terminal alkyne functional group. This unique bifunctional structure makes it a valuable intermediate for advanced organic synthesis, enabling the construction of complex molecular architectures. It is primarily utilized in research and development for pharmaceuticals, agrochemicals, and advanced material science, where precise molecular assembly is critical.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the synthesis of active pharmaceutical ingredients (APIs) and novel drug candidates, particularly in click chemistry and cross-coupling reactions.
• Agrochemical Synthesis: Used in the development of new pesticides, herbicides, and plant growth regulators that require specific alkyne-chloro alkane chains.
• Material Science Research: Acts as a monomer or cross-linking agent in the development of specialty polymers, dendrimers, and functionalized surfaces.
• Liquid Crystal & OLED Materials: Employed in the synthesis of organic semiconductors and liquid crystal compounds for electronic displays.
• Chemical Biology Probes: Useful for labeling and bioconjugation applications due to its reactive alkyne group, which can participate in Huisgen cycloaddition.
• Organic Synthesis Reagent: A versatile reagent for introducing a long-chain alkyne moiety with a handle for further functionalization via nucleophilic substitution of the chloride.

Basic Information

Product Name	1-Chloro-5-Dodecyne
CAS No.	35087-20-8
Molecular Formula	C₁₂H₂₁Cl
Molecular Weight	200.75 g/mol
Synonyms	5-Dodecyn-1-yl chloride; 1-Chloro-5-dodecyne; 5-Chloro-1-dodecyne; Dodec-5-yn-1-yl chloride; Chlorododecyne; 1-Chlorododec-5-yne
EINECS	Contact for details

Quality Control

Our 1-Chloro-5-Dodecyne is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing including GC, HPLC, and NMR to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support cGMP and ISO 9001 standards for reliable supply to regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and oxidizing agents. For long-term storage, consider maintaining under an inert atmosphere such as nitrogen to preserve stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.