Description

Prajmaline CAS NO 35080-11-6 is a potent class Ia antiarrhythmic agent, chemically classified as an ajmaline derivative. This compound is critical for pharmaceutical research and development, particularly in the study and treatment of cardiac arrhythmias. It is primarily required by pharmaceutical manufacturers, R&D laboratories, and academic institutions engaged in cardiovascular drug discovery and synthesis.

Application

• Pharmaceutical Active Ingredient (API): Serves as a key intermediate or active component in the formulation of antiarrhythmic medications.
• Biochemical Research: Used as a reference standard and tool compound in cardiac electrophysiology studies to investigate sodium channel blockade.
• Pharmacology & Toxicology: Employed in preclinical studies to evaluate efficacy, pharmacokinetics, and safety profiles of antiarrhythmic agents.
• Analytical Standard: Essential for quality control laboratories as a high-purity certified reference material (CRM) for HPLC, LC-MS, or NMR analysis.
• Academic Research: Utilized in university and institutional research projects focused on cardiovascular disease mechanisms and novel therapeutic pathways.
• Chemical Synthesis: Acts as a sophisticated building block for the synthetic modification and development of new ajmaline analogs with improved properties.

Basic Information

Product Name	Prajmaline
CAS No.	35080-11-6
Molecular Formula	C27H34N2O4
Molecular Weight	450.57 g/mol
Synonyms	N-Propylajmalinium; Prajmalium; N-Propylajmaline; Prajmaline Bitartrate; NPAB; 17-Monochloroacetylajmaline; GT 1012; Prajmalinum
EINECS	Contact for details

Quality Control

Our Prajmaline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling via advanced techniques like HPLC and NMR to ensure it meets high-grade standards suitable for research and pharmaceutical applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with specified parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.