Description

Hydroxydehydro Nifedipine Carboxylate is a key pharmaceutical intermediate and chemical building block. This compound is of significant value in the research and development of advanced active pharmaceutical ingredients (APIs), particularly in the cardiovascular and related therapeutic areas. It is primarily utilized by pharmaceutical manufacturers, R&D laboratories, and fine chemical synthesis specialists for the production of high-value target molecules.

Application

• Pharmaceutical Intermediate: Critical building block in the synthesis of nifedipine analogs and other dihydropyridine-based calcium channel blockers.
• Active Pharmaceutical Ingredient (API) Research: Serves as a precursor in the development and scale-up of novel cardiovascular drugs.
• Chemical Synthesis: Used in organic synthesis for constructing complex molecular architectures requiring its specific carboxylate and hydroxydehydro functional groups.
• Reference Standard: Employed as a high-purity analytical standard in quality control (QC) and research laboratories for method development and validation.
• Process Chemistry: Integral in optimizing manufacturing routes for cost-effective and scalable production of target pharmaceuticals.

Basic Information

Product Name	Hydroxydehydro Nifedipine Carboxylate
CAS No.	34783-31-8
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	1,4-Dihydro-2,6-dimethyl-4-(2-nitrophenyl)-3,5-pyridinedicarboxylic acid, 5-(hydroxymethyl) methyl ester; 5-(Hydroxymethyl) Nifedipine; Hydroxydehydro Nifedipine; Nifedipine Impurity; Nifedipine Related Compound; 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(2-nitrophenyl)-, 5-(hydroxymethyl) methyl ester; Methyl 1,4-dihydro-2,6-dimethyl-4-(2-nitrophenyl)-5-(hydroxymethyl)pyridine-3-carboxylate
EINECS	Contact for details

Quality Control

Our Hydroxydehydro Nifedipine Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for pharmaceutical intermediates. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms
Identification (HPLC)	Conforms
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.