Description

2,4,6-Trimethylphenylacetonitrile is a versatile aromatic nitrile building block, also known as Mesitylacetonitrile. This compound is valued for its sterically hindered phenyl group, which makes it a crucial intermediate in the synthesis of complex molecules. It is primarily sought after by R&D chemists and process development teams in the pharmaceutical and agrochemical industries for constructing advanced chemical architectures.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring sterically hindered aromatic systems.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides where the mesityl group imparts specific biological activity and stability.
• Ligand and Catalyst Preparation: Serves as a precursor for the synthesis of specialized phosphine and nitrogen-based ligands used in homogeneous catalysis.
• Material Science Research: Employed in the development of organic semiconductors, liquid crystals, and advanced polymers due to its rigid molecular structure.
• Fine Chemical Synthesis: A versatile starting material for creating dyes, pigments, and other performance chemicals requiring specific aromatic substitution patterns.

Basic Information

Product Name	2,4,6-Trimethylphenylacetonitrile
CAS No.	34688-71-6
Molecular Formula	C11H13N
Molecular Weight	159.23 g/mol
Synonyms	Mesitylacetonitrile; (2,4,6-Trimethylphenyl)acetonitrile; α-Mesitylacetonitrile; 2-(2,4,6-Trimethylphenyl)acetonitrile; Mesityleneacetonitrile; NSC 403116; (Mesityl)acetonitrile
EINECS	Contact for details

Quality Control

Our 2,4,6-Trimethylphenylacetonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chromatographic purity analysis and identity confirmation, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) detailing all specifications are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.