Description

2-Bromo-4-Nitrobenzonitrile is a versatile halogenated aromatic nitrile building block, essential for advanced organic synthesis. Its unique structure, featuring both an electron-withdrawing nitro group and a reactive bromine atom, makes it a critical intermediate for constructing complex molecules. This compound is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a substituted benzonitrile core.
• Agrochemical Synthesis: Used in the development of herbicides, fungicides, and insecticides, where the nitro and bromo functionalities enable diverse chemical modifications.
• Material Science Research: Serves as a monomer or building block for creating specialized polymers, liquid crystals, and organic electronic materials.
• Dye and Pigment Manufacturing: Acts as an intermediate in the production of complex azo dyes and high-performance pigments.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for Suzuki, Heck, and other palladium-catalyzed cross-coupling reactions to form biaryl structures.
• Organic Synthesis Reagent: Employed in academic and industrial R&D labs for constructing complex heterocycles and other aromatic compounds.

Basic Information

Product Name	2-Bromo-4-Nitrobenzonitrile
CAS No.	34662-35-6
Molecular Formula	C7H3BrN2O2
Molecular Weight	227.02 g/mol
Synonyms	4-Nitro-2-bromobenzonitrile; 2-Bromo-4-nitrobenzenecarbonitrile; Benzonitrile, 2-bromo-4-nitro-; NSC 403119; 2-Bromo-4-cyanomitrobenzene; 2-Bromo-4-nitro-phenyl cyanide; o-Bromo-p-nitrobenzonitrile
EINECS	Contact for details

Quality Control

Every batch of 2-Bromo-4-Nitrobenzonitrile is manufactured and tested under a strict quality management system to ensure consistency and reliability for your synthesis. We provide comprehensive analytical data, including HPLC purity, identity confirmation (IR, NMR), and impurity profiling. A Certificate of Analysis (COA) is supplied with each shipment, detailing all relevant specifications to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture. Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	145 - 149 °C
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.