Description

4-Chloro-2-Nitrobenzonitrile is a versatile halogenated nitrile compound that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both an electron-withdrawing nitro group and a reactive chloro substituent on the benzonitrile core, makes it a valuable intermediate for constructing complex molecules. This compound is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of various active pharmaceutical ingredients (APIs), particularly those with heterocyclic structures.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and insecticides, leveraging its reactive sites for molecular diversification.
• Dye and Pigment Manufacturing: Serves as a starting material for synthesizing complex organic dyes and colorants.
• Material Science Research: Employed in the development of advanced polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: Acts as a substrate in palladium-catalyzed reactions (e.g., Suzuki, Heck) for creating biaryl structures.
• Nucleophilic Aromatic Substitution: The chloro and nitro groups make it an excellent candidate for SNAr reactions to introduce new functional groups.

Basic Information

Product Name	4-Chloro-2-Nitrobenzonitrile
CAS No.	34662-32-3
Molecular Formula	C7H3ClN2O2
Molecular Weight	182.56 g/mol
Synonyms	2-Nitro-4-chlorobenzonitrile; 4-Chloro-2-nitrobenzenecarbonitrile; Benzonitrile, 4-chloro-2-nitro-; 4-Chloro-2-nitro-phenyl cyanide; NSC 403119; 2-Cyano-5-chloronitrobenzene; 5-Chloro-2-nitrobenzonitrile
EINECS	Contact for details

Quality Control

Our 4-Chloro-2-Nitrobenzonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive and should be stored away from direct light exposure.

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	118°C - 122°C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.