Description

5-Chloro-2-Nitrobenzonitrile is a versatile aromatic nitrile derivative that serves as a critical building block in advanced organic synthesis. Its molecular structure, featuring both chloro and nitro substituents, makes it a valuable precursor for constructing complex molecules, particularly in the pharmaceutical and agrochemical sectors. This high-purity intermediate is essential for research chemists and process development teams working on active pharmaceutical ingredients (APIs), crop protection agents, and specialty dyes.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of various drug candidates, particularly those with benzamide or aniline cores.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and insecticides, leveraging its reactive nitro and cyano groups.
• Dye and Pigment Manufacturing: Acts as a precursor for azo dyes and other complex colorants due to its aromatic nitro functionality.
• Material Science Research: Employed in the development of organic semiconductors, liquid crystals, and polymers.
• Cross-Coupling Reactions: Serves as a substrate in palladium-catalyzed reactions like Suzuki or Buchwald-Hartwig amination for C-C and C-N bond formation.
• Chemical Research & Development: A valuable reagent for exploring novel heterocyclic compounds and other fine chemical entities.

Basic Information

Product Name	5-Chloro-2-Nitrobenzonitrile
CAS No.	34662-31-2
Molecular Formula	C7H3ClN2O2
Molecular Weight	182.56 g/mol
Synonyms	2-Nitro-5-chlorobenzonitrile; 5-Chloro-2-nitrobenzenecarbonitrile; Benzonitrile, 5-chloro-2-nitro-; 34662-31-2; 5-Chloro-2-nitro-benzonitrile; 2-Cyano-4-chloronitrobenzene; 4-Chloro-2-cyanointrobenzene
EINECS	Contact for details

Quality Control

Our 5-Chloro-2-Nitrobenzonitrile is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support cGMP standards for pharmaceutical applications and can accommodate custom purity requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This material is light-sensitive and should be stored away from direct light. It is also easily oxidized; for long-term storage, consider keeping under an inert atmosphere such as nitrogen or argon. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	118 - 122 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.