Description

3-Chloro-5-Nitrobenzonitrile is a versatile aromatic nitrile derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both electron-withdrawing chloro and nitro substituents, makes it a valuable intermediate for constructing complex molecules with specific electronic and steric properties. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to create novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a substituted benzonitrile core.
• Agrochemical Synthesis: Used in the development of herbicides, fungicides, and insecticides, where the nitrile and nitro groups contribute to biological activity.
• Material Science Research: Serves as a monomer or functionalization agent in the creation of specialty polymers, liquid crystals, and organic electronic materials.
• Dye and Pigment Manufacturing: Acts as an intermediate for producing complex azo dyes and other high-performance colorants.
• Cross-Coupling Reactions: A valuable substrate in palladium-catalyzed reactions (e.g., Suzuki, Sonogashira) for creating biaryl structures common in many advanced compounds.
• Chemical Research & Development: Employed in academic and industrial labs for methodological studies and the exploration of new reaction pathways involving halogenated nitroarenes.

Basic Information

Product Name	3-Chloro-5-Nitrobenzonitrile
CAS No.	34662-30-1
Molecular Formula	C7H3ClN2O2
Molecular Weight	182.56 g/mol
Synonyms	5-Nitro-3-chlorobenzonitrile; 3-Chloro-5-nitrobenzenecarbonitrile; Benzonitrile, 3-chloro-5-nitro-; 1-Chloro-3-cyano-5-nitrobenzene; NSC 403119; 3-Chloro-5-nitro-benzonitrile; 3-Chloro-5-nitrobenzonitrile (GC grade)
EINECS	Contact for details

Quality Control

Our 3-Chloro-5-Nitrobenzonitrile is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for synthetic applications. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and consistency for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases, reducing agents, and sources of ignition. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	118 - 122 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.