Description

Boc-Asp-Otbu CAS NO 34582-32-6 is a protected aspartic acid derivative, specifically the tert-butyl ester of N-tert-butoxycarbonyl-L-aspartic acid. This compound is a crucial building block in solid-phase peptide synthesis (SPPS), enabling the controlled incorporation of aspartic acid while preventing unwanted side reactions. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and life sciences sectors developing therapeutic peptides, APIs, and complex organic molecules.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key protected amino acid derivative for the sequential assembly of peptide chains.
• Pharmaceutical Intermediates: Serves as a critical precursor in the synthesis of peptide-based active pharmaceutical ingredients (APIs).
• Bioconjugation: Used in the modification of proteins and other biomolecules where a protected carboxylic acid group is required.
• Organic Synthesis: Acts as a chiral synthon for constructing complex molecules in medicinal chemistry and chemical biology research.
• Research & Development: Fundamental reagent in academic and industrial R&D labs for exploring new peptide structures and functions.

Basic Information

Product Name	Boc-Asp-Otbu
CAS No.	34582-32-6
Molecular Formula	C₁₃H₂₃NO₆
Molecular Weight	289.32 g/mol
Synonyms	N-(tert-Butoxycarbonyl)-L-aspartic acid 4-tert-butyl ester; Boc-L-aspartic acid β-tert-butyl ester; Boc-Asp(OtBu)-OH; (2S)-2-[(2-Methylpropan-2-yl)oxycarbonylamino]butanedioic acid 4-tert-butyl ester; N-Boc-L-aspartic acid 4-tert-butyl ester; Boc-Aspart(OtBu)-OH; tert-Butyl N-[(1S)-3-tert-butoxy-1-(carboxymethyl)-3-oxopropyl]carbamate
EINECS	Contact for details

Quality Control

Our Boc-Asp-Otbu is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral integrity, to ensure it meets the high standards required for peptide synthesis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and specific impurities is provided with every shipment to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.5%
Optical Rotation	-15.0° to -18.0° (c=1 in AcOH)
Chiral Purity (HPLC)	≥99.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.