Description

4-Fluorophenyl Acetic Hydrazide is a high-purity fluorinated aromatic hydrazide derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its bifunctional reactivity, where the hydrazide group acts as a versatile nucleophile and the fluorinated aromatic ring provides enhanced stability and unique electronic properties for downstream products. This compound is essential for research and production chemists in the pharmaceutical, agrochemical, and specialty chemical industries, particularly for the synthesis of heterocycles, active pharmaceutical ingredients (APIs), and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of various heterocyclic compounds, including pyrazoles, triazoles, and other nitrogen-containing pharmacophores with potential biological activity.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and plant growth regulators, leveraging the fluorine atom for improved metabolic stability and bioavailability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized chelating ligands and organocatalysts used in asymmetric synthesis and metal complexation.
• Polymer and Material Science: Acts as a monomer or cross-linking agent in the production of specialty polymers, resins, and high-performance materials with tailored thermal and chemical resistance.
• Chemical Research & Development: A valuable reagent for method development, scale-up studies, and exploring new reaction pathways in academic and industrial R&D laboratories.
• Dye and Pigment Industry: Intermediate for synthesizing fluorinated dyes and pigments, where the fluorine substituent can alter color fastness and spectral properties.

Basic Information

Product Name	4-Fluorophenyl Acetic Hydrazide
CAS No.	34547-28-9
Molecular Formula	C8H9FN2O
Molecular Weight	168.17 g/mol
Synonyms	2-(4-Fluorophenyl)acetohydrazide; (4-Fluorophenyl)acetic acid hydrazide; p-Fluorophenylacetic hydrazide; 4-Fluorobenzeneacetic acid hydrazide; 34547-28-9; NSC 403697; 2-(4-Fluorophenyl)acetylhydrazine
EINECS	Contact for details

Quality Control

Our 4-Fluorophenyl Acetic Hydrazide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles where applicable, ensuring reliability for your most demanding synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is easily oxidized and should be handled under an inert atmosphere for long-term storage or when opening sealed containers. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	142 - 147 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.