Description

Boc-D-Glu-Oh CAS NO 34404-28-9 is a high-purity, protected amino acid derivative, specifically the N-tert-butoxycarbonyl derivative of D-glutamic acid. This compound is a critical chiral building block in the synthesis of complex peptides and peptidomimetics, offering precise stereochemical control. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical industries engaged in developing novel therapeutic agents and bioactive molecules.

Application

• Pharmaceutical Intermediates: Key chiral synthon for the solid-phase and solution-phase synthesis of peptide-based drugs and active pharmaceutical ingredients (APIs).
• Peptide Research: Fundamental building block for constructing custom peptides with D-amino acids to enhance metabolic stability and biological activity.
• Bioconjugation: Used in the preparation of labeled peptides and protein conjugates for diagnostic and research applications.
• Combinatorial Chemistry: A valuable reagent in libraries for drug discovery and high-throughput screening campaigns.
• Fine Chemical Synthesis: Intermediate in the synthesis of more complex organic molecules requiring a protected glutamic acid moiety.

Basic Information

Product Name	Boc-D-Glu-Oh
CAS No.	34404-28-9
Molecular Formula	C₁₀H₁₇NO₆
Molecular Weight	247.24 g/mol
Synonyms	N-(tert-Butoxycarbonyl)-D-glutamic Acid; (R)-2-((tert-Butoxycarbonyl)amino)pentanedioic Acid; Boc-D-Glutamic Acid; BOC-D-GLU-OH; N-Boc-D-glutamic acid; D-Glutamic acid, N-[(1,1-dimethylethoxy)carbonyl]-; N-tert-Butoxycarbonyl-D-glutamic Acid
EINECS	Contact for details

Quality Control

Our Boc-D-Glu-Oh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and identity confirmation by IR and NMR spectroscopy. We provide Certificates of Analysis (COA) with detailed specifications to ensure compliance with your research and production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.