Description

10-[2-(Dimethylamino)Propyl]-N,n-Dimethyl-10H-Phenothiazine-2-Sulphonamide Monohydrochloride is a high-purity phenothiazine derivative, a critical intermediate in advanced pharmaceutical synthesis. This compound matters for its role in the development of active pharmaceutical ingredients (APIs) with specific neurological and therapeutic effects. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the synthesis of novel drug candidates, particularly within the central nervous system (CNS) therapeutic area.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel phenothiazine-based active pharmaceutical ingredients (APIs).
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and the development of new therapeutic agents.
• Neurological Drug Synthesis: Serves as a precursor in the manufacture of compounds targeting central nervous system (CNS) disorders.
• Chemical Reference Standard: Employed as a high-purity standard in analytical laboratories for method development and quality control.
• Specialty Fine Chemical Production: Utilized in the multi-step synthesis of complex, high-value organic molecules for various applications.

Basic Information

Product Name	10-[2-(Dimethylamino)Propyl]-N,n-Dimethyl-10H-Phenothiazine-2-Sulphonamide Monohydrochloride
CAS No.	34396-64-0
Molecular Formula	C19H26N4O2S2·HCl
Molecular Weight	451.02 g/mol
Synonyms	Promethazine Sulphonamide Hydrochloride; 2-Sulfamoyl-N,N-dimethyl-10-[2-(N,N-dimethylamino)propyl]phenothiazine-10-ium chloride; N,N-Dimethyl-1-(10H-phenothiazin-10-yl)-2-propanamine 2-sulfonamide monohydrochloride; Promethazine-2-sulfonamide hydrochloride; 10H-Phenothiazine-10-ethanamine, N,N,α-trimethyl-, 2-sulfonamide, monohydrochloride; NSC 113927; Phenothiazine-2-sulfonamide derivative hydrochloride
EINECS	Contact for details

Quality Control

Our 10-[2-(Dimethylamino)Propyl]-N,n-Dimethyl-10H-Phenothiazine-2-Sulphonamide Monohydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets exacting standards for pharmaceutical intermediate applications. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.