Description

13-cis-Retinyl Acetate is a specific geometric isomer of vitamin A acetate, a critical compound in the synthesis of biologically active retinoids. Its precise stereochemistry makes it a valuable intermediate for pharmaceutical research and development, particularly in dermatology and oncology. This high-purity compound is essential for manufacturers and research institutions focused on creating novel retinoid-based therapies, cosmetic actives, and advanced nutritional formulations.

Application

• Pharmaceutical Intermediate: Key starting material for the synthesis of isotretinoin (13-cis-retinoic acid) and other therapeutic retinoids used in acne treatment and cancer research.
• Cosmetic & Dermatological R&D: Used in the development of advanced anti-aging, skin-repair, and acne-treatment formulations to study retinoid efficacy and stability.
• Biochemical Research: Serves as a standard and reagent in studies of vitamin A metabolism, cell differentiation, and gene expression regulated by retinoid receptors.
• Nutraceutical Development: Employed in the research of stable, bioavailable vitamin A derivatives for specialized dietary supplements.
• Reference Standard: Used as a high-purity chromatographic reference standard in quality control laboratories for pharmaceutical and cosmetic products.

Basic Information

Product Name	13-cis-Retinyl Acetate
CAS No.	34356-31-5
Molecular Formula	C22H32O2
Molecular Weight	328.49 g/mol
Synonyms	13-cis-Vitamin A Acetate; (13Z)-Retinyl Acetate; Isotretinoin Acetate; 13-cis-Retinol Acetate; all-trans-Retinyl Acetate Isomer; 13-Z-Retinyl Acetate; Vitamin A Acetate (13-cis-isomer); 3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraen-1-ol Acetate (13-cis)
EINECS	Contact for details

Quality Control

Our 13-cis-Retinyl Acetate is manufactured under strict quality systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity and isomer specificity, to ensure it meets the stringent requirements for research and pharmaceutical intermediate use. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee identity, purity, and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C or as specified on the label. This product is strictly light-sensitive and easily oxidized; prolonged exposure to air, light, or elevated temperatures should be avoided to maintain stability.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder or solid
Identification (HPLC/IR)	Conforms to standard
Assay (HPLC)	≥98.0%
Isomeric Purity (13-cis)	≥95.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Solvent Residues (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.