Description

n-Piperidin-4-Yl-Benzamide CAS NO 33953-37-6 is a high-purity benzamide derivative featuring a piperidine moiety, serving as a critical synthetic intermediate in advanced organic chemistry. Its value lies in providing a versatile and reliable building block for constructing complex molecular architectures, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries who require precise and consistent raw materials for their synthesis pipelines.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, due to the bioactive piperidine scaffold.
• Medicinal Chemistry Research: Used extensively in hit-to-lead and lead optimization campaigns for constructing compound libraries and exploring structure-activity relationships (SAR).
• Agrochemical Synthesis: Serves as a building block for developing new active ingredients in crop protection products, such as herbicides and fungicides.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Fine Chemical Production: Employed in the multi-step synthesis of specialty chemicals, dyes, and performance materials requiring specific amide functionalities.
• Academic & Contract Research: A valuable reagent for universities and CROs (Contract Research Organizations) conducting fundamental and applied chemical research.

Basic Information

Item	Details
Product Name	n-Piperidin-4-Yl-Benzamide
CAS No.	33953-37-6
Molecular Formula	C12H16N2O
Molecular Weight	204.27 g/mol
Synonyms	4-(Benzoylamino)piperidine; 1-(4-Piperidinyl)-1H-benzimidazole (incorrect but common misnomer); N-(Piperidin-4-yl)benzamide; Benzamide, N-4-piperidinyl-; 4-Benzamidopiperidine; 4-Aminopiperidine benzamide; Piperidin-4-yl-benzamide; N-(4-Piperidyl)benzamide
EINECS	Contact for details

Quality Control

Our n-Piperidin-4-Yl-Benzamide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring the material meets the stringent requirements for pharmaceutical R&D and other high-value applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and handling properties. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.