Description

(S)-6-(Acetylamino)-3-[[(S)-3,6-Bis(Acetylamino)Hexanoyl]Amino]Hexanoic Acid Methyl Ester is a high-purity, chiral synthetic intermediate of significant importance in advanced pharmaceutical research and development. Its value lies in its role as a sophisticated building block for constructing complex peptide-like molecules and active pharmaceutical ingredients (APIs). This compound is primarily needed by pharmaceutical companies, biotechnology firms, and contract research organizations (CROs) engaged in the synthesis of novel therapeutics, particularly in areas requiring high stereochemical purity.

Application

• Pharmaceutical Intermediate: A critical chiral building block for the synthesis of complex peptide-based drugs and novel active pharmaceutical ingredients (APIs).
• Protease Inhibitor Research: Used in the development and study of enzyme inhibitors targeting specific proteolytic pathways.
• Chemical Biology Probes: Serves as a key component in the creation of molecular probes for studying protein-protein interactions and cellular mechanisms.
• Peptidomimetic Synthesis: Integral to the design and production of peptidomimetics, which are molecules that mimic peptides but with enhanced stability and bioavailability.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high stereochemical fidelity.
• Academic & Institutional Research: Utilized in university and institutional labs for fundamental research in medicinal chemistry and organic synthesis methodologies.

Basic Information

Product Name	(S)-6-(Acetylamino)-3-[[(S)-3,6-Bis(Acetylamino)Hexanoyl]Amino]Hexanoic Acid Methyl Ester
CAS No.	33861-54-0
Molecular Formula	C19H34N4O6
Molecular Weight	414.50 g/mol
Synonyms	Methyl (3S,6S)-6-acetamido-3-[(3S,6S)-3,6-bis(acetamido)hexanamido]hexanoate; Nα-Acetyl-Nε-[(S)-3,6-bis(acetylamino)hexanoyl]-L-lysine methyl ester; L-Lysine, N2-acetyl-N6-[(3S,6S)-3,6-bis(acetylamino)-1-oxohexyl]-, methyl ester; A chiral tripeptide mimetic methyl ester; Ac-Lys(Ac-Ahx-Ac-NH2)-OMe (abbreviated form); A protected lysine derivative
EINECS	Contact for details

Quality Control

Our production of (S)-6-(Acetylamino)-3-[[(S)-3,6-Bis(Acetylamino)Hexanoyl]Amino]Hexanoic Acid Methyl Ester adheres to stringent quality management systems, ensuring batch-to-batch consistency and high chemical purity suitable for research and development applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing key parameters such as chiral purity, chemical purity (HPLC), and identity confirmation. We operate under a cGMP-compliant mindset for pharmaceutical intermediates, and specifications can be aligned with client requirements for advanced projects.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as specified on the label or COA. The compound may be hygroscopic (moisture-sensitive); therefore, the container should be kept in a dry environment. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.