Description

Bis(Pentafluorophenyl)-1-Propynylphosphine is a highly fluorinated organophosphorus compound characterized by its unique pentafluorophenyl and propynyl substituents. This specialized phosphine ligand is valued for its strong electron-withdrawing properties and steric profile, which are critical for modulating catalyst activity and selectivity in advanced chemical synthesis. It is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and materials science industries for developing novel catalytic processes and high-performance materials.

Application

• Catalyst Ligand in Cross-Coupling Reactions: Serves as a sophisticated ligand for palladium, nickel, and other transition metal catalysts in demanding C-C and C-X bond-forming reactions, such as Suzuki, Heck, and Sonogashira couplings.
• Advanced Material Synthesis: Employed in the research and development of specialized polymers, fluorinated materials, and electronic chemicals where its fluorinated structure imparts desired properties like thermal stability and chemical resistance.
• Pharmaceutical Intermediate Manufacturing: Used in the synthesis of complex, fluorinated active pharmaceutical ingredients (APIs) where precise control over stereochemistry and reaction pathways is essential.
• Agrochemical Research: Acts as a key building block or catalyst component in the development of novel, high-performance crop protection agents.
• Academic & Industrial R&D: A valuable reagent for exploring new methodologies in organometallic chemistry and catalysis within university and corporate research laboratories.

Basic Information

Product Name	Bis(Pentafluorophenyl)-1-Propynylphosphine
CAS No.	33730-52-8
Molecular Formula	C21H5F10P
Molecular Weight	502.22 g/mol
Synonyms	1-Propynylbis(2,3,4,5,6-pentafluorophenyl)phosphine; Bis(2,3,4,5,6-pentafluorophenyl)(1-propynyl)phosphine; (1-Propynyl)bis(pentafluorophenyl)phosphine; P,P-Bis(pentafluorophenyl)-P-prop-1-yn-1-ylphosphine; Fluorinated propynylphosphine ligand; BPPFP
EINECS	Contact for details

Quality Control

Every batch of Bis(Pentafluorophenyl)-1-Propynylphosphine is produced and analyzed under strict quality management protocols to ensure consistency and high purity for research and development applications. Our standard quality commitment includes comprehensive analysis via NMR (1H, 19F, 31P) and HPLC to verify identity and purity. A detailed Certificate of Analysis (COA) documenting all test results is provided with each shipment to support your quality assurance processes.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C in a cool, dry, well-ventilated place. Keep away from heat, sparks, and open flame. Due to its sensitivity to oxidation and moisture, containers should be purged with inert gas after each opening.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
31P NMR Purity	≥ 95.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.