Description

(3,3-Dimethyl-1-Butynyl)Diphenylphosphine is a specialized organophosphorus ligand and synthetic building block. This compound matters for its role in facilitating key catalytic transformations, particularly in the synthesis of complex organic molecules and advanced materials. It is primarily needed by researchers and process chemists in the pharmaceutical, agrochemical, and fine chemical industries for developing new synthetic routes and optimizing catalytic processes.

Application

• Catalytic Ligand in Cross-Coupling Reactions: Used as a supporting ligand in palladium- or nickel-catalyzed reactions such as Suzuki, Heck, and Sonogashira couplings for C-C bond formation.
• Organic Synthesis Intermediate: Serves as a key precursor in the synthesis of more complex phosphine ligands and functionalized organophosphorus compounds.
• Material Science Research: Employed in the development of novel metal-organic frameworks (MOFs), polymers, and other advanced materials where phosphorus-based coordination is required.
• Pharmaceutical Development: Utilized in the research and scale-up of active pharmaceutical ingredients (APIs) that require sophisticated phosphine-mediated catalytic steps.
• Asymmetric Catalysis: Investigated for use in creating chiral environments for enantioselective synthesis, important for producing single-isomer drug molecules.

Basic Information

Product Name	(3,3-Dimethyl-1-Butynyl)Diphenylphosphine
CAS No.	33730-51-7
Molecular Formula	C18H19P
Molecular Weight	266.32 g/mol
Synonyms	Diphenyl(3,3-dimethylbut-1-yn-1-yl)phosphine; (3,3-Dimethyl-1-butyn-1-yl)diphenylphosphine; 1-(Diphenylphosphino)-3,3-dimethyl-1-butyne; Neopentylidynephosphine derivative; Tert-butylacetylene-diphenylphosphine adduct
EINECS	Contact for details

Quality Control

Our (3,3-Dimethyl-1-Butynyl)Diphenylphosphine is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including NMR, HPLC, and elemental analysis, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. Due to its sensitivity to oxidation, containers should be kept sealed and purged after each use to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.