Description

1-Cyano-8-Fluoronaphthalene is a specialized fluorinated naphthalene derivative that serves as a high-value intermediate in advanced chemical synthesis. This compound is engineered to provide a unique combination of a cyano group and a fluorine atom on the naphthalene scaffold, offering precise reactivity for constructing complex molecular architectures. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting fluorinated bioactive molecules.
• Agrochemical Research: Used in the development of advanced pesticides and herbicides, where the fluorine atom enhances biological activity and environmental stability.
• Organic Light-Emitting Diode (OLED) Materials: Serves as a precursor for electron-transport or host materials in the manufacture of high-performance display and lighting technologies.
• Liquid Crystal & Functional Material Synthesis: Employed in creating fluorinated components for liquid crystal displays (LCDs) and other advanced organic electronic materials.
• Cross-Coupling Reactions: Acts as a versatile substrate in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) for constructing biaryl systems.
• Academic & Industrial R&D: A valuable reagent for methodological studies in organic synthesis and fluorochemistry within university and corporate research laboratories.

Basic Information

Product Name	1-Cyano-8-Fluoronaphthalene
CAS No.	33718-13-7
Molecular Formula	C₁₁H₆FN
Molecular Weight	171.17 g/mol
Synonyms	8-Fluoro-1-naphthalenecarbonitrile; 8-Fluoronaphthalene-1-carbonitrile; 1-Cyano-8-fluoronaphthalene; 8-Fluoro-1-cyanonaphthalene; NSC 339063; 1-Naphthalenecarbonitrile, 8-fluoro-; 8-Fluoro-1-naphthonitrile
EINECS	Contact for details

Quality Control

Our 1-Cyano-8-Fluoronaphthalene is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and relevant industry standards for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.