Description

Cefoxitin Sodium CAS NO 33564-30-6 is a second-generation, semi-synthetic cephamycin antibiotic derived from cephamycin C. It is valued for its broad-spectrum bactericidal activity, particularly against anaerobic bacteria and β-lactamase-producing strains. This compound is a critical active pharmaceutical ingredient (API) primarily required by pharmaceutical manufacturers for the production of injectable antibiotic formulations.

Application

• Pharmaceutical API: Primary use as the active ingredient in sterile injectable antibiotic products.
• Hospital & Clinical Formulations: Used in the preparation of solutions for intravenous or intramuscular administration to treat serious infections.
• Surgical Prophylaxis: Key component in antibiotics administered pre- and post-operatively to prevent surgical site infections, particularly in colorectal and obstetric-gynecologic surgeries.
• Treatment of Polymicrobial Infections: Effective against mixed aerobic and anaerobic infections, such as intra-abdominal abscesses, peritonitis, and pelvic inflammatory disease.
• Research & Development: Serves as a reference standard and building block in microbiological research and the development of new antimicrobial agents.
• Veterinary Medicine: Used in certain high-value veterinary applications for treating bacterial infections in animals.

Basic Information

Product Name	Cefoxitin Sodium
CAS No.	33564-30-6
Molecular Formula	C16H16N3NaO7S2
Molecular Weight	449.43 g/mol
Synonyms	Cefoxitin Sodium Salt; Sodium Cefoxitin; (6R,7S)-3-(Carbamoyloxymethyl)-7-methoxy-8-oxo-7-[(2-thienylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate Sodium Salt; Mefoxin (Brand Name); Cefoxitin Na; Cefoxitin Sodium USP; 7-Methoxycephalosporin; Cefoxitin Sodium Sterile
EINECS	251-583-5

Quality Control

Our Cefoxitin Sodium is manufactured and tested to meet stringent pharmacopeial standards, including USP and EP monographs. Every batch undergoes comprehensive analytical testing for identity, potency, purity, and microbiological quality. A Certificate of Analysis (COA) documenting results for assay, related substances, residual solvents, water content, and sterility (where applicable) is provided to ensure full traceability and compliance with cGMP guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C) or as specified on the label. This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms
Identification (HPLC)	Conforms
Assay (HPLC)	96.0% - 102.0% (on anhydrous basis)
pH (1% Solution)	4.0 - 7.0
Water Content (KF)	≤ 5.0%
Related Substances (HPLC)	Individual Impurity: ≤ 1.0% Total Impurities: ≤ 3.0%
Residual Solvents (GC)	Complies with ICH Q3C
Bacterial Endotoxins	< 0.10 EU/mg
Sterility (for sterile grade)	Sterile

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.