Description

H-Val-NH2 HBr is a high-purity, protected amino acid derivative, specifically the hydrobromide salt of H-Val-NH2. This compound is a critical building block in the synthesis of complex peptides and active pharmaceutical ingredients (APIs), offering excellent stability and handling properties. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and advanced chemical synthesis sectors who require reliable, high-quality intermediates for drug discovery and development.

Application

• Pharmaceutical Intermediate: A key raw material in the synthesis of peptide-based drugs and therapeutic agents.
• Peptide Synthesis: Used as a protected valine derivative in solid-phase and solution-phase peptide synthesis (SPPS).
• Bioconjugation: Serves as a linker or spacer molecule in the development of antibody-drug conjugates (ADCs) and other bioconjugates.
• Research & Development: A valuable reagent in academic and industrial R&D for exploring new bioactive peptides and peptidomimetics.
• Chemical Biology: Employed in the study of protein-protein interactions and enzyme mechanisms.
• Custom Synthesis: A starting material for the custom manufacturing of specialized amino acid derivatives and fine chemicals.

Basic Information

Product Name	H-Val-NH2 HBr
CAS No.	33529-85-0
Molecular Formula	C5H13N2O2•HBr
Molecular Weight	225.08 g/mol
Synonyms	L-Valinamide hydrobromide; Valinamide HBr; H-Val-NH2•HBr; 2-Amino-3-methylbutanamide hydrobromide; (S)-2-Amino-3-methylbutanamide hydrobromide; Val-NH2•HBr; Boc-Val-NH2 deprotection product; Amino-protected valine amide salt
EINECS	Contact for details

Quality Control

Our H-Val-NH2 HBr is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and residual solvent screening, to ensure it meets the high standards required for pharmaceutical applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability, consistency, and compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. Keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Optical Rotation	[α]20/D: +15° to +25° (c=1 in H2O)
Chiral Purity (HPLC)	≥99.0%
Loss on Drying	≤1.0%
Heavy Metals	≤20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.