Description

3'-Demethyl-12-Deoxyerythromycin is a key semi-synthetic derivative of the macrolide antibiotic erythromycin. This compound serves as a crucial intermediate in the synthesis of advanced antibiotic agents, offering researchers and manufacturers a versatile building block for developing novel therapeutics. It is primarily utilized by pharmaceutical R&D teams and fine chemical producers focused on antibiotic innovation and process chemistry.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of next-generation macrolide antibiotics with improved pharmacological profiles.
• Antibacterial Research: Used in microbiological and medicinal chemistry research to study structure-activity relationships (SAR) and develop new antibacterial agents.
• Process Chemistry: Employed in the scale-up and optimization of synthetic routes for complex antibiotic molecules in fine chemical manufacturing.
• Reference Standard: Serves as a high-purity analytical standard for quality control and regulatory testing in pharmaceutical production.
• Academic & Institutional Research: Utilized in university and institutional labs for studies related to antibiotic resistance and drug discovery.

Basic Information

Product Name	3'-Demethyl-12-Deoxyerythromycin
CAS No.	33442-56-7
Molecular Formula	C36H65NO12
Molecular Weight	703.90 g/mol
Synonyms	12-Deoxy-3'-demethylerythromycin; 3'-O-Demethyl-12-deoxyerythromycin; 12-Deoxyerythromycin C; (3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-4-[(2,6-Dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl)oxy]-14-ethyl-7,12,13-trihydroxy-3,5,7,9,11,13-hexamethyl-6-[[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy]oxacyclotetradecane-2,10-dione
EINECS	Contact for details

Quality Control

Our 3'-Demethyl-12-Deoxyerythromycin is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical intermediate applications. Certificates of Analysis (COA) documenting all critical quality attributes are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 5.0% Any single impurity ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.