Description

Aprindine Hcl CAS NO 33237-74-0 is a high-purity pharmaceutical intermediate and active pharmaceutical ingredient (API) of significant commercial importance. This compound is valued for its critical role in the synthesis of antiarrhythmic medications, where consistent quality and purity are paramount. It is primarily required by pharmaceutical manufacturers, research institutions, and fine chemical suppliers engaged in cardiovascular drug development and production.

Application

• Pharmaceutical API: Serves as the active pharmaceutical ingredient in the formulation of antiarrhythmic drugs for the treatment of cardiac arrhythmias.
• Chemical Synthesis Intermediate: A key building block in the multi-step synthesis of complex cardiovascular therapeutic agents.
• Biochemical Research: Used in pharmacological and biochemical studies to investigate sodium channel blocking mechanisms and cardiac electrophysiology.
• Reference Standard: Employed as a high-purity analytical standard in quality control laboratories for method development and validation in pharmaceutical analysis.
• Fine Chemical Production: Utilized by specialty chemical manufacturers for the production of derivatives and related compounds for medical research.

Basic Information

Product Name	Aprindine Hcl
CAS No.	33237-74-0
Molecular Formula	C22H30N2•HCl
Molecular Weight	358.95 g/mol
Synonyms	Aprindine Hydrochloride; N-(3-Diethylamino-2,2-dimethylpropyl)-N-phenyl-2-indanamine Hydrochloride; Amidonal; Fibocil; Fiboran; 1-[2,3-Dihydro-1H-inden-2-yl]-N,N-diethyl-N-phenyl-3-propylamine Hydrochloride
EINECS	Contact for details

Quality Control

Our Aprindine Hcl is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets stringent specifications for identity, purity, and potency, suitable for pharmaceutical applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with relevant standards. We support audits and can provide documentation for regulatory submissions.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed to prevent degradation from moisture and light exposure.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	98.0% - 102.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 1.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.